DESARROLLARON UN NOVEDOSO MÉTODO PARA “ESPIAR” MICROESTRUCTURAS EN TEJIDOS BIOLÓGICOS
Un equipo de científicos en el que participa un docente del Instituto Balseiro desarrolló un novedoso método que permite generar nuevas formas de imágenes a partir de resonancia magnética nuclear (RMN). Así, los investigadores lograron mapear información morfológica de sistemas químicos y biológicos a una escala menor a la tradicional. El trabajo fue publicado en una de las revistas del grupo Nature, “Scientific Reports”.
Internal gradient distributions: A susceptibility-derived tensor delivering morphologies by magnetic resonance | Scientific Reports
Gonzalo A. Álvarez, Noam Shemesh & Lucio Frydman
Scientific Reports 7, 3311 (2017)
Nuclear magnetic resonance is a powerful tool for probing the structures of chemical and biological systems. Combined with field gradients it leads to NMR imaging (MRI), a widespread tool in non-invasive examinations. Sensitivity usually limits MRI’s spatial resolution to tens of micrometers, but other sources of information like those delivered by constrained diffusion processes, enable one extract morphological information down to micron and sub-micron scales. We report here on a new method that also exploits diffusion – isotropic or anisotropic– to sense morphological parameters in the nm-mm range, based on distributions of susceptibility-induced magnetic field gradients. A theoretical framework is developed to define this source of information, leading to the proposition of internal gradient-distribution tensors. Gradient-based spin-echo sequences are designed to measure these new observables. These methods can be used to map orientations even when dealing with unconstrained diffusion, as is here demonstrated with studies of structured systems, including tissues.
Colloquium: Protecting quantum information against environmental noise
Dieter Suter and Gonzalo A. Álvarez
Rev. Mod. Phys. 88, 041001 (2016)
Published 10 October 2016
Quantum-mechanical systems retain their properties so long as the phase of quantum superpositions evolve stably over time. Contact with an environment can disrupt this phase evolution. But for environments that do not exchange energy with the quantum system, strategies exist where the controlled driving of the system can recover or maintain the quantum phase. This Colloquium surveys the host of techniques that are available to “refocus” the phase when disturbed by various forms of classical or quantum environment. While the first such techniques were developed long ago, ideas from quantum information theory have introduced new strategies for accomplishing this goal.
Quantum state transfer in disordered spin chains: How much engineering is reasonable? | Quant. Inf. Comm. (2015)
Analia Zwick, Gonzalo A. Álvarez, Joachim Stolze, and Omar Osenda
The transmission of quantum states through spin chains is an important element in the im- plementation of quantum information technologies. Speed and fidelity of transfer are the main objectives which have to be achieved by the devices even in the presence of imperfections which are unavoidable in any manufacturing process. To reach these goals, several kinds of spin chains have been suggested, which differ in the degree of fine-tuning, or engineering, of the system parameters. In this work we present a systematic study of two important classes of such chains. In one class only the spin couplings at the ends of the chain have to be adjusted to a value different from the bulk coupling constant, while in the other class every coupling has to have a specific value. We demonstrate that configurations from the two different classes may perform similarly when subjected to the same kind of disorder in spite of the large difference in the engineering effort necessary to prepare the system. We identify the system features responsible for these similarities and we perform a detailed study of the transfer fidelity as a function of chain length and disorder strength, yielding empirical scaling laws for the fidelity which are similar for all kinds of chain and all dis- order models. These results are helpful in identifying the optimal spin chain for a given quantum information transfer task. In particular, they help in judging whether it is worthwhile to engineer all couplings in the chain as compared to adjusting only the boundary couplings.
Optimized dynamical control of state transfer through noisy spin chains
Analia Zwick, Gonzalo A Álvarez, Guy Bensky and Gershon Kurizki
Focus on Coherent Control of Complex Quantum Systems:
New J. Phys. 16, 065021 (2014).
We propose a method of optimally controlling the tradeoff of speed and fidelity of state transfer through a noisy quantum channel spin-chain. This process is treated as qubit state-transfer through a fermionic bath. We show that dynamical modulation of the boundary-qubits levels can ensure state transfer with the best tradeoff of speed and fidelity. This is achievable by dynamically optimizing the transmission spectrum of the channel. The resulting optimal control is robust against both static and fluctuating noise in the channelʼs spin–spin couplings. It may also facilitate transfer in the presence of diagonal disorder on site energy noise in the channel.
Diffusion-assisted selective dynamical recoupling: A new approach to measure background gradients in magnetic resonance | J. Chem. Phys. (2014)
Diffusion-assisted selective dynamical recoupling: A new approach to measure background gradients in magnetic resonance
Gonzalo A. Álvarez, Noam Shemesh and Lucio Frydman
J. Chem. Phys. 140, 084205 (2014); http://dx.doi.org/10.1063/1.4865335
Dynamical decoupling, a generalization of the original NMR spin-echo sequence, is becoming increasingly relevant as a tool for reducing decoherence in quantum systems. Such sequences apply non-equidistant refocusing pulses for optimizing the coupling between systems, and environmental fluctuations characterized by a given noise spectrum. One such sequence, dubbed Selective Dynamical Recoupling SDR [P. E. S. Smith, G. Bensky, G. A. Álvarez, G. Kurizki, and L. Frydman, Proc. Natl. Acad. Sci. 109, 5958 (2012)], allows one to coherently reintroduce diffusion decoherence effects driven by fluctuations arising from restricted molecular diffusion [G. A. Álvarez, N. Shemesh, and L. Frydman, Phys. Rev. Lett. 111, 080404 (2013)]. The fully-refocused, constant-time, and constant-number-of-pulses nature of SDR also allows one to filter out “intrinsic” T1 and T2 weightings, as well as pulse errors acting as additional sources of decoherence. This article explores such features when the fluctuations are now driven by unrestricted molecular diffusion. In particular, we show that diffusion-driven SDR can be exploited to investigate the decoherence arising from the frequency fluctuations imposed by internal gradients. As a result, SDR presents a unique way of probing and characterizing these internal magnetic fields, given an a priori known free diffusion coefficient. This has important implications in studies of structured systems, including porous media and live tissues, where the internal gradients may serve as fingerprints for the systems composition or structure. The principles of this method, along with full analytical solutions for the unrestricted diffusion-driven modulation of the SDR signal, are presented. The potential of this approach is demonstrated with the generation of a novel source of MRI contrast, based on the background gradients active in an ex vivo mouse brain. Additional features and limitations of this new method are discussed.
© 2014 AIP Publishing LLC
Quantum simulations of localization effects with dipolar interactions
Gonzalo A. Álvarez, Robin Kaiser, Dieter Suter
Quantum information processing often uses systems with dipolar interactions. Here a nuclear spin-based quantum simulator is used to study the spreading of information in such a dipolar-coupled system. While the information spreads with no apparent limits in the case of ideal dipolar couplings, additional perturbations limit the spreading, leading to localization. In previous work [Phys. Rev. Lett. 104, 230403 (2010)], it was found that the system size reaches a dynamic equilibrium that decreases with the square of the perturbation strength. This work examines the impact of a disordered Hamiltonian with dipolar interactions. It shows that the expansion of the cluster of spins freezes in the presence of large disorder, reminiscent of Anderson localization of non-interacting waves in a disordered potential.
Keywords: spin dynamics;dipolar interaction;decoherence;localization;disorder;NMR;long range interactions;quantum information processing
Annalen der Physik
Special Issue on “Quantum Simulations“, featuring review papers written by last year’s Nobel Prize winners describing their foundational work (Wineland and Haroche). Issue edited by: Rainer Blatt, Immanuel Bloch, Ignacio Cirac, Peter Zoller.
Ann. Phys. 525, 833 (2013).
© 2013 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim